Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603362 | 0.88 | GPR35 (0.44) | TSHRGPR35MEN1KMT2APOLB | |
| SCHEMBL1653003 | 0.88 | GPR35 (0.44) | TSHRGPR35MEN1KMT2APOLB | |
| SCHEMBL28062163 | 0.87 | KMT2A (0.53) | HCAR3MEN1KMT2APOLBCYP2C9 | |
| SCHEMBL8722580 | 0.87 | PLK1 (0.42) | HCAR3TSHRGPR35MEN1KMT2A | |
| SCHEMBL1695820 | 0.86 | GPR35 (0.43) | TSHRGPR35MEN1KMT2APOLB | |
| SCHEMBL15303188 | 0.85 | ALDH1A1 (0.46) | HCAR3KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL1652977 | 0.84 | FNTA (0.45) | SMN1; SMN2NPSR1LMNAALDH1A1MAPT | |
| SCHEMBL1652970 | 0.83 | KMT2A (0.47) | HCAR3SMN1; SMN2TSHRGPR35MEN1 | |
| SCHEMBL1653848 | 0.82 | ALDH1A1 (0.46) | GPR35MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10974753 | 0.82 | ALDH1A1 (0.54) | HCAR3TSHRGPR35MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524788-B1 | Process for lysing liposome membrane | WAKO PURE CHEM IND LTD (JP) | 1997-02-12 | — | — | EP | disclosed |
| US-5501953-A | MIXING WITH SURFACTANTS, AVIDIN AND BIOTIN FOR MARKING AND RELEASING | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0524788-A1 | Process for lysing liposome membrane | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1993-01-27 | — | — | EP | disclosed |