SCHEMBL8749908

SCHEMBL8749908

C=C(C)C(=O)OCCOCC[Si](OC)(OC)OC

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.58
TSHR P16473 6/20 0.43
ALDH1A1 P00352 5/20 0.38
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TP53 P04637 2/20 0.33
HIF1A Q16665 2/20 0.33
HSD17B10 Q99714 1/20 0.33
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2502772 0.90 THRB (0.54) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL183781 0.89 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL976767 0.83 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL5959895 0.83 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9314009 0.83 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL672102 0.83 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7157722 0.83 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL22166147 0.83 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4950550 0.83 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4617966 0.83 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528978-B2 Water-based dispersion floor adhesive with high dimensional stability SIKA TECHNOLOGY AG (CH) 2026-01-20 US disclosed
US-12325810-B2 Water-based composition with chemical cross-linking SIKA TECHNOLOGY AG (CH) 2025-06-10 US disclosed
US-20250162953-A1 USE OF ADHESIVES, SEALANTS, OR COATINGS ON GREEN CONCRETE AND OTHER HIGHLY ALKALINE SUBSTRATES SIKA TECHNOLOGY AG (CH) 2025-05-22 US disclosed
EP-3713898-B1 WATER-BASED 2-COMPONENT COMPOSITION WITH CHEMICAL CURING SIKA TECH AG (CH) 2025-03-19 EP disclosed
EP-4496783-A1 USE OF ADHESIVES, SEALANTS, OR COATINGS ON GREEN CONCRETE AND OTHER HIGHLY ALKALINE SUBSTRATES Sika Technology AG (CH) 2025-01-29 EP disclosed
CN-118900829-A Use of adhesives, sealants or coatings on green concrete and other highly alkaline substrates SIKA技术股份公司 2024-11-05 CN disclosed
CN-115087696-B Water-based dispersion floor adhesive with high dimensional stability SIKA技术股份公司 2024-09-06 CN disclosed
US-11981605-B2 Two-component water-based cementitious adhesive with reduced viscosity SIKA TECHNOLOGY AG (CH) 2024-05-14 US disclosed
EP-3818125-B1 WATER-BASED COMPOSITION WITH CHEMICAL CROSS-LINKING SIKA TECH AG (CH) 2024-05-08 EP disclosed
US-11873421-B2 Water-based composition with improved transparency SIKA TECHNOLOGY AG (CH) 2024-01-16 US disclosed
WO-2020187854-A1 WATER-BASED COMPOSITION WITH IMPROVED TRANSPARENCY SIKA TECHNOLOGY AG (CH) 2020-09-24 WO disclosed
CN-111344266-A Chemically curing water-based 2-component compositions SIKA技术股份公司 2020-06-26 CN disclosed
WO-2020007765-A1 WATER-BASED COMPOSITION WITH CHEMICAL CROSS-LINKING SIKA TECHNOLOGY AG (CH) 2020-01-09 WO disclosed
EP-3551691-A1 WATER-BASED COMPOSITION WITH LOW SURFACE TACKINESS Sika Technology AG (CH) 2019-10-16 EP disclosed
US-20190292424-A1 WATER-BASED COMPOSITION WITH LOW SURFACE TACKINESS SIKA TECHNOLOGY AG (CH) 2019-09-26 US disclosed
WO-2019101740-A1 WATER-BASED 2-COMPONENT COMPOSITION WITH CHEMICAL CURING SIKA TECHNOLOGY AG (CH) 2019-05-31 WO disclosed
WO-2018108629-A1 WATER-BASED COMPOSITION WITH LOW SURFACE TACKINESS SIKA TECHNOLOGY AG (CH) 2018-06-21 WO disclosed
EP-3333218-A1 WATER-BASED COMPOSITION WITH LOW SURFACE TACKINESS Sika Technology AG (CH) 2018-06-13 EP disclosed
EP-0587332-B1 Acrylic caulking or sealing composition ROHM & HAAS (US) 1997-03-26 EP disclosed
EP-0587332-A1 Acrylic caulking or sealing composition ROHM AND HAAS COMPANY (US) 1994-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528978-B2 Water-based dispersion floor adhesive with high dimensional stability ZW10, VCL, H1-10 THRB 4777/4885TSHR 3992/4885ALDH1A1 1644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.