Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | XPO1 | O14980 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15842585 | 0.83 | CA12 (0.60) | CA12MAOAPTGS1ALDH1A1KDM4E | |
| SCHEMBL12299958 | 0.77 | PTGS1 (0.74) | CA12MAOAPTGS1ALDH1A1KDM4E | |
| SCHEMBL8750107 | 0.76 | ALDH1A1 (0.48) | CA12MAOAALDH1A1KDM4EHPGD | |
| SCHEMBL8750130 | 0.76 | CA12 (0.60) | CA12MAOAPTGS1ALDH1A1KDM4E | |
| SCHEMBL8750110 | 0.73 | CYP2A6 (0.45) | MAOAALDH1A1KDM4EHPGDMCL1 | |
| SCHEMBL11253029 | 0.73 | MAOA (0.59) | CA12MAOAPTGS1ALDH1A1KDM4E | |
| SCHEMBL8750163 | 0.72 | XPO1 (0.64) | CA12ALDH1A1KDM4EHPGDCA9 | |
| SCHEMBL8750123 | 0.71 | CA12 (0.47) | CA12MAOAALDH1A1KDM4EHPGD | |
| SCHEMBL836924 | 0.71 | CYP2A6 (0.59) | CA12MAOAALDH1A1KDM4EHPGD | |
| SCHEMBL11271517 | 0.71 | ALDH1A1 (0.59) | CA12MAOAPTGS1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639893-A | Process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | claimed |
| EP-0757989-A1 | A process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | claimed |
| US-5639893-A | Process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0757989-A1 | A process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |