SCHEMBL8750407

SCHEMBL8750407

CC(OC(C)c1ccc(C(C)(C)c2ccccc2)cc1)c1ccc(C(C)(C)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
ESR1 P03372 4/20 0.50
ESR2 Q92731 4/20 0.50
CYP3A4 P08684 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.42
NR3C2 P08235 3/20 0.41
MAPK1 P28482 1/20 0.40
KDM4E B2RXH2 5/20 0.39
TDP1 Q9NUW8 1/20 0.39
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
HTT P42858 2/20 0.38
ALOX15 P16050 1/20 0.38
GAA P10253 1/20 0.38
AR P10275 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
HTR6 P50406 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8750637 0.86 ALDH1A1 (0.48) ALDH1A1ESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL6546771 0.81 ESR1 (0.56) ALDH1A1ESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL11129493 0.80 ESR1 (0.50) ALDH1A1ESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL198133 0.78 HCAR2 (0.45) ALDH1A1KDM4ETSHR
SCHEMBL8750389 0.78 ESR1 (0.57) ALDH1A1ESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL22223039 0.78 ESR1 (0.52) ALDH1A1ESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL8750404 0.78 ESR1 (0.52) ALDH1A1ESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL7535051 0.78 ESR1 (0.75) ALDH1A1ESR1ESR2CYP3A4SMN1; SMN2
Hydrochloric Acid SCHEMBL2231581 0.76 PDE2A (0.53) ALDH1A1ESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL17511150 0.76 ALDH1A1 (0.42) ALDH1A1ESR1ESR2CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523697-B1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS (JP) 1997-04-02 EP disclosed
US-5447901-A Color-developing sheet: base material coated with composition of /a/ multivalent metal-modified salicylic acid resin formed from salicylic acid, a benzyl compound and optional styrene and /b/ analogous resin free of salicylic acid MITSUI TOATSU CHEMICAL, INC. (JP) 1995-09-05 US disclosed
US-5376615-A Pressure sensitive elements containing a salicylic acid resin and a phenolic resin MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-12-27 US disclosed
EP-0523697-A1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed