SCHEMBL8750413

SCHEMBL8750413

CC(OC(C)c1ccc(C(C)c2ccccc2)cc1)c1ccc(C(C)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
PDCD1 Q15116 1/20 0.42
ESR2 Q92731 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
HCAR2 Q8TDS4 1/20 0.40
TYR P14679 1/20 0.38
TAAR1 Q96RJ0 3/20 0.38
ADRA2A P08913 2/20 0.38
ADRA2C P18825 2/20 0.38
ADRA2B P18089 1/20 0.38
KMT2A Q03164 1/20 0.37
CYP2D6 P10635 1/20 0.37
LMNA P02545 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALOX5 P09917 1/20 0.37
DAO P14920 1/20 0.36
ALDH1A1 P00352 1/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL198133 0.90 HCAR2 (0.45) HCAR2TAAR1ADRA2AADRA2CADRA2B
Phosphine SCHEMBL20897413 0.87 CYP2D6 (0.46) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL8643448 0.84 ESR1 (0.55) ESR1PDCD1ESR2CD274TYR
SCHEMBL9069753 0.84 ESR1 (0.41) ESR1PDCD1ESR2CD274HCAR2
SCHEMBL8750423 0.83 PTGS2 (0.43) PDCD1CD274HCAR2TAAR1ADRA2A
SCHEMBL169730 0.82 TAAR1 (0.50) ESR1PDCD1ESR2CD274TYR
SCHEMBL7499823 0.82 TAAR1 (0.50) ESR1PDCD1ESR2CD274TYR
SCHEMBL8750420 0.81 PTGS2 (0.52) PDCD1CD274ALDH1A1
SCHEMBL104838 0.80 HCAR2 (0.42) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL13554105 0.80 HCAR2 (0.42) HCAR2TAAR1ADRA2AADRA2CADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523697-B1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS (JP) 1997-04-02 EP disclosed
EP-0268878-B1 Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents MITSUI TOATSU CHEMICALS (JP) 1996-01-31 EP disclosed
US-5447901-A Color-developing sheet: base material coated with composition of /a/ multivalent metal-modified salicylic acid resin formed from salicylic acid, a benzyl compound and optional styrene and /b/ analogous resin free of salicylic acid MITSUI TOATSU CHEMICAL, INC. (JP) 1995-09-05 US disclosed
US-5376615-A Pressure sensitive elements containing a salicylic acid resin and a phenolic resin MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-12-27 US disclosed
EP-0523697-A1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed
US-5023366-A Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-06-11 US disclosed
EP-0268878-A2 Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-01 EP disclosed