SCHEMBL8750423

SCHEMBL8750423

CC(OC(C)c1ccccc1)c1ccccc1.c1cc2ccc1-2

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.43
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
CYP1A2 P05177 1/20 0.39
GAA P10253 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
CYP2C19 P33261 1/20 0.39
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
TAAR1 Q96RJ0 2/20 0.39
ADRA2A P08913 2/20 0.39
ADRA2C P18825 2/20 0.39
ADRA2B P18089 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP2D6 P10635 1/20 0.38
LMNA P02545 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8750420 0.93 PTGS2 (0.52) PTGS2CHRNB2CHRNA4CYP1A2GAA
SCHEMBL198133 0.92 HCAR2 (0.45) HCAR2TAAR1ADRA2AADRA2CADRA2B
Ammonia Solution, Strong SCHEMBL27871924 0.90 HCAR2 (0.44) HCAR2TAAR1ADRA2AADRA2CADRA2B
Phosphine SCHEMBL20897413 0.90 CYP2D6 (0.46) HCAR2TAAR1ADRA2AADRA2CADRA2B
Hydrochloric Acid SCHEMBL28273439 0.90 ALDH1A1 (0.44) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL8750413 0.83 ESR1 (0.42) HCAR2PDCD1CD274TAAR1ADRA2A
SCHEMBL3163758 0.82 HCAR2 (0.42) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL13554105 0.82 HCAR2 (0.42) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL104838 0.82 HCAR2 (0.42) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL17367389 0.82 HCAR2 (0.42) HCAR2TAAR1ADRA2AADRA2CADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523697-B1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS (JP) 1997-04-02 EP disclosed
US-5447901-A Color-developing sheet: base material coated with composition of /a/ multivalent metal-modified salicylic acid resin formed from salicylic acid, a benzyl compound and optional styrene and /b/ analogous resin free of salicylic acid MITSUI TOATSU CHEMICAL, INC. (JP) 1995-09-05 US disclosed
US-5376615-A Pressure sensitive elements containing a salicylic acid resin and a phenolic resin MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-12-27 US disclosed
EP-0523697-A1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed