SCHEMBL8750495

SCHEMBL8750495

CCC(=O)C(C(=O)OC)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ZDHHC7 Q9NXF8 1/20 0.38
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
CA14 Q9ULX7 2/20 0.34
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP13 P45452 1/20 0.32
CA12 O43570 1/20 0.32
ACHE P22303 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2202426 0.95 SMN1; SMN2 (0.40) SMN1; SMN2CA1CA2ZDHHC7MGAM
SCHEMBL7533050 0.88 CA1 (0.36) SMN1; SMN2CA1CA2ZDHHC7MGAM
SCHEMBL10485422 0.88 CA1 (0.36) SMN1; SMN2CA1CA2ZDHHC7MGAM
SCHEMBL1363735 0.79 SOAT1 (0.48) MGAMGAASIMGAM2SOAT1
SCHEMBL20931300 0.77 CA1 (0.39) SMN1; SMN2CA1CA2ZDHHC7CA14
SCHEMBL31201800 0.77 MGAM (0.46) SMN1; SMN2CA1CA2ZDHHC7MGAM
SCHEMBL114574 0.77 SMN1; SMN2 (0.41) SMN1; SMN2CA1CA2ZDHHC7MGAM
SCHEMBL422851 0.76 SMN1; SMN2 (0.53) SMN1; SMN2CA1CA2ZDHHC7MGAM
SCHEMBL13668427 0.76 TDP1 (0.44) SOAT1ALDH1A1TSHRKMT2AFFAR3
SCHEMBL1398170 0.75 CA1 (0.38) SMN1; SMN2CA1CA2ZDHHC7MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0367132-B1 Light-sensitive composition BASF AG (DE) 1997-04-02 EP claimed
US-5034305-A Mixtures for photoresists of water insolublr binders soluble in alkaline mixtures, compound forming a strong acid and solubility inhibitors BASF AKTIENGESELLSCHAFT (DE) 1991-07-23 US claimed
EP-0367132-A2 Light-sensitive composition BASF Aktiengesellschaft (DE) 1990-05-09 EP claimed
EP-0367132-B1 Light-sensitive composition BASF AG (DE) 1997-04-02 EP disclosed
US-5034305-A Mixtures for photoresists of water insolublr binders soluble in alkaline mixtures, compound forming a strong acid and solubility inhibitors BASF AKTIENGESELLSCHAFT (DE) 1991-07-23 US disclosed