Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750569 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MAPTDUSP3PTPN5 | |
| SCHEMBL8755410 | 0.91 | FAAH (0.38) | SMN1; SMN2ALDH1A1MAPTDUSP3PTPN5 | |
| SCHEMBL8952484 | 0.88 | MGLL (0.46) | — | |
| SCHEMBL8755504 | 0.88 | MGLL (0.46) | — | |
| SCHEMBL8707756 | 0.84 | NPC1 (0.48) | CHRM3 | |
| SCHEMBL9233369 | 0.84 | NPC1 (0.48) | CHRM3 | |
| SCHEMBL9230089 | 0.84 | NPC1 (0.43) | SMN1; SMN2ALDH1A1MAPTDUSP3PTPN5 | |
| SCHEMBL8757603 | 0.84 | EPHX1 (0.39) | SMN1; SMN2ALDH1A1MAPTDUSP3PTPN5 | |
| SCHEMBL9682837 | 0.82 | NPC1 (0.54) | CHRM3 | |
| SCHEMBL9542179 | 0.82 | NPC1 (0.54) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765312-A1 | 4-CARBAMOYLOXY-PIPERIDINE-1-CARBOXYLIC ACID ESTERS: INHIBITORS OF CHOLESTEROL ABSORPTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-04-02 | — | — | EP | disclosed |
| US-5527804-A | 4-carbamoyloxy-piperidine-1-carboxylic acid esters: inhibitors or cholesterol absorption | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| WO-1995034539-A1 | 4-CARBAMOYLOXY-PIPERIDINE-1-CARBOXYLIC ACID ESTERS: INHIBITORS OF CHOLESTEROL ABSORPTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-12-21 | — | — | WO | disclosed |