Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750916 | 0.94 | CTSL (0.62) | CTSLCTSSCTSBCTSKCAPN1 | |
| SCHEMBL5308284 | 0.85 | CTSL (0.58) | CTSLCTSSCTSBCTSKSIRT2 | |
| SCHEMBL8236608 | 0.85 | CTSL (0.58) | CTSLCTSSCTSBCTSKSIRT2 | |
| SCHEMBL5298109 | 0.82 | SIRT2 (0.54) | CTSLCTSSCTSBCTSKTGM2 | |
| SCHEMBL8192271 | 0.82 | CAPN1 (0.53) | CTSLCTSSCTSBCTSKCAPN1 | |
| SCHEMBL22599593 | 0.81 | CTSL (0.70) | CTSLCTSSCTSBCTSKCAPN1 | |
| SCHEMBL9113871 | 0.81 | CTSL (0.73) | CTSLCTSSCTSBCTSKCAPN1 | |
| SCHEMBL6621545 | 0.80 | HTT (0.60) | TGM2 | |
| SCHEMBL6361024 | 0.80 | SIRT2 (0.62) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL6361021 | 0.80 | SIRT2 (0.62) | CTSLCTSSSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764151-A2 | PURIFICATION OF SERINE PROTEASE AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034538-A2 | PURIFICATION OF SERINE PROTEASES AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1995-12-21 | — | — | WO | disclosed |