Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138550 | 0.85 | KMT2A (0.43) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL869265 | 0.80 | MAPT (0.64) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL869266 | 0.80 | MAPT (0.64) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL7665404 | 0.76 | MAPT (0.53) | LMNAALDH1A1KMT2AMAPTHDAC3 | |
| SCHEMBL4790312 | 0.76 | LMNA (0.58) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL4790316 | 0.76 | LMNA (0.58) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL8750906 | 0.75 | LMNA (0.47) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL7667994 | 0.74 | LMNA (0.69) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL27901596 | 0.74 | LMNA (0.69) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| Ethyl Cinnamate SCHEMBL28097609 | 0.73 | CA12 (0.59) | LMNAAKR1B10AKR1B1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539601-B1 | CINNAMIC ACID/GLYCEROL ADDUCT, ULTRAVIOLET ABSORBER, AND DERMATOLOGIC PREPARATION | SHISEIDO CO LTD (JP) | 1997-04-09 | — | — | EP | disclosed |
| US-5426210-A | Water soluble sunscreen agents | SHISEIDO CO., LTD. (JP) | 1995-06-20 | — | — | US | disclosed |
| EP-0539601-A1 | CINNAMIC ACID/GLYCEROL ADDUCT, ULTRAVIOLET ABSORBER, AND DERMATOLOGIC PREPARATION | SHISEIDO COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |