SCHEMBL8750962

SCHEMBL8750962

CCCCCCCCCCc1ncc(-c2ccc(O)c(F)c2)cn1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.51
FAAH O00519 2/20 0.51
CNR1 P21554 2/20 0.51
RARB P10826 2/20 0.45
RARA P10276 1/20 0.45
RARG P13631 1/20 0.45
CYP17A1 P05093 2/20 0.42
MAPT P10636 2/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
ALOX5 P09917 1/20 0.41
TYR P14679 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 1/20 0.41
STAT3 P40763 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8750999 1.00 MGLL (0.51) MGLLFAAHCNR1RARBRARA
SCHEMBL9399538 0.84 RARB (0.43) MGLLFAAHCNR1RARBRARA
SCHEMBL9398886 0.83 RARB (0.41) RARBRARARARGMAPTCYP3A4
SCHEMBL9740614 0.82 MAPT (0.54) MGLLFAAHCNR1RARBRARA
SCHEMBL6249433 0.82 MAPT (0.54) MGLLFAAHCNR1RARBRARA
SCHEMBL6250464 0.82 MAPT (0.54) MGLLFAAHCNR1RARBRARA
SCHEMBL9399953 0.81 S1PR1 (0.43) MGLLRARBRARARARGMAPT
SCHEMBL9398905 0.81 S1PR1 (0.45) MGLLRARBRARARARG
SCHEMBL7090423 0.80 RARB (0.59) MGLLFAAHCNR1RARBRARA
SCHEMBL8024671 0.80 RARB (0.68) MGLLFAAHCNR1RARBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3221589-A None JP disclosed
EP-0460624-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1997-09-10 EP disclosed
EP-0440136-B1 Liquid crystal composition and liquid crystal device containing the same CANON KK (JP) 1997-04-02 EP disclosed
US-5391318-A Liquid crystal composition and liquid crystal device containing the same CANON KABUSHIKI KAISHA (JP) 1995-02-21 US disclosed
US-5269964-A Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1993-12-14 US disclosed
EP-0460624-A2 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1991-12-11 EP disclosed
JP-H03221589-A FERROELECTRIC CHIRAL SMECTIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT CONTAINING SAME COMPOSITION CANON INC 1991-09-30 JP disclosed
EP-0440136-A2 Liquid crystal composition and liquid crystal device containing the same CANON KABUSHIKI KAISHA (JP) 1991-08-07 EP disclosed