Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895476 | 0.93 | TSHR (0.66) | TSHRSMN1; SMN2ALDH1A1KMT2AESR1 | |
| SCHEMBL8059189 | 0.87 | CYP1A2 (0.68) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28540163 | 0.87 | TSHR (0.61) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL20457819 | 0.87 | TSHR (0.66) | TSHRCYP1A2CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL8257957 | 0.86 | TSHR (0.58) | TSHRCYP2D6CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL13450827 | 0.85 | TSHR (0.57) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13037029 | 0.85 | TSHR (0.57) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17863562 | 0.84 | MMP13 (0.61) | TSHRSMN1; SMN2ALDH1A1MMP13LMNA | |
| SCHEMBL17346792 | 0.84 | TSHR (0.53) | TSHRSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL1720194 | 0.83 | ALDH1A1 (0.67) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609786-B1 | Process for producing urethane compound | MITSUBISHI GAS CHEMICAL CO (JP) | 1997-04-09 | — | — | EP | disclosed |
| US-5391805-A | Process for producing urethane compound | MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0609786-A1 | Process for producing urethane compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-08-10 | — | — | EP | disclosed |
| EP-0436800-B1 | Process for producing isocyanate compound | MITSUBISHI GAS CHEMICAL CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-5166414-A | Process for producing isocyanate compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0436800-A1 | Process for producing isocyanate compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-07-17 | — | — | EP | disclosed |