Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239489 | 0.82 | DRD2 (0.41) | OPRM1OPRK1OPRL1DRD2OPRD1 | |
| SCHEMBL21944503 | 0.82 | DRD2 (0.41) | OPRM1OPRK1OPRL1DRD2OPRD1 | |
| SCHEMBL1764933 | 0.81 | HTR2A (0.50) | OPRM1OPRK1OPRL1DRD2OPRD1 | |
| SCHEMBL15093858 | 0.81 | HTR2A (0.50) | OPRM1OPRK1OPRL1DRD2OPRD1 | |
| SCHEMBL15093618 | 0.81 | HTR2A (0.50) | OPRM1OPRK1OPRL1DRD2OPRD1 | |
| SCHEMBL8959911 | 0.81 | OPRM1 (0.43) | OPRM1OPRK1OPRL1DRD2OPRD1 | |
| SCHEMBL19525073 | 0.81 | OPRM1 (0.44) | OPRM1OPRK1OPRL1DRD2OPRD1 | |
| SCHEMBL13144705 | 0.80 | OPRM1 (0.45) | OPRM1OPRK1OPRL1OPRD1SLC6A2 | |
| Hydrochloric Acid SCHEMBL10754178 | 0.80 | HTR2A (0.48) | OPRM1OPRK1OPRL1DRD2OPRD1 | |
| Bromide SCHEMBL7252604 | 0.80 | HTR2A (0.48) | OPRM1OPRK1OPRL1DRD2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766562-A1 | THERAPEUTICAL COMPOSITIONS COMPRISING 3-PHENYL-3-HYDROXYPIPERIDINES | LABORATOIRE L. LAFON (FR) | 1997-04-09 | — | — | EP | disclosed |
| EP-0691956-A1 | 3-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEDATIVES | LABORATOIRE L. LAFON (FR) | 1996-01-17 | — | — | EP | disclosed |
| WO-1996000064-A1 | THERAPEUTICAL COMPOSITIONS COMPRISING 3-PHENYL-3-HYDROXYPIPERIDINES | LABORATOIRE L. LAFON (FR) | 1996-01-04 | — | — | WO | disclosed |
| WO-1994022827-A1 | 3-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEDATIVES | LABORATOIRE L. LAFON (FR) | 1994-10-13 | — | — | WO | disclosed |