Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.76 |
| ▸ | MMP2 | P08253 | 5/20 | 0.76 |
| ▸ | MMP9 | P14780 | 5/20 | 0.76 |
| ▸ | EGFR | P00533 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8751546 | 1.00 | MMP1 (0.76) | MMP1MMP2MMP9EGFRMAPT | |
| N-(4-Methoxyphenyl)Cinnamamide SCHEMBL4131114 | 0.87 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| 4-Methoxy-Cinnamanilide SCHEMBL14375152 | 0.87 | MMP1 (0.89) | MMP1MMP2MMP9EGFRMAPT | |
| N-(4-Methoxyphenyl)Cinnamamide SCHEMBL9094893 | 0.87 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| N-(4-Methoxyphenyl)Cinnamamide SCHEMBL4131112 | 0.87 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL17693073 | 0.85 | MAPT (0.88) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL31338544 | 0.85 | RAB9A (0.71) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL11299307 | 0.83 | MMP1 (0.92) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL8751515 | 0.83 | MAPT (0.77) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL8751492 | 0.83 | MAPT (0.77) | MMP1MMP2MMP9EGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541737-B1 | N-PHENYL-CINNAMAMIDES PROVIDING PROTECTION FROM THE HARMFUL EFFECTS OF ULTRAVIOLET LIGHT | BAUDET PIERRE (CH) | 1997-04-09 | — | — | EP | disclosed |