Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936243 | 0.83 | CYP2D6 (0.43) | LMNAMTORMEN1KMT2AGAA | |
| SCHEMBL290984 | 0.78 | LMNA (0.46) | LMNACYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL11324526 | 0.78 | LMNA (0.42) | LMNACYP2C19CYP2D6ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1752733 | 0.76 | LMNA (0.45) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL19711879 | 0.76 | LMNA (0.37) | LMNACYP2C19MTORMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28251812 | 0.75 | LMNA (0.44) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4842428 | 0.74 | CYP2C19 (0.42) | LMNACYP2C19MTOR | |
| SCHEMBL4843912 | 0.74 | CYP2C19 (0.42) | LMNACYP2C19MTOR | |
| SCHEMBL18493238 | 0.73 | TAAR1 (0.39) | LMNACYP2C19ALDH1A1KDM4ETDP1 | |
| SCHEMBL30518068 | 0.73 | SLC6A2 (0.42) | LMNAMEN1KMT2ASRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829447-A | Brush prodrug and use thereof | 麻省理工学院 | 2022-07-29 | — | — | CN | disclosed |
| EP-0628542-B1 | Process for the preparation of organic carbamates | BAYER AG (DE) | 1997-04-09 | — | — | EP | disclosed |
| EP-0628542-A1 | Process for the preparation of organic carbonates | BAYER AG (DE) | 1994-12-14 | — | — | EP | disclosed |