Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 3/20 | 0.40 |
| ▸ | HRH1 known ✓ | P35367 | 3/20 | 0.40 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28251812 | 0.98 | LMNA (0.44) | LMNATDP1KDM4EALDH1A1HTR2A | |
| SCHEMBL290984 | 0.98 | LMNA (0.46) | LMNATDP1KDM4EALDH1A1HTR2A | |
| SCHEMBL11324526 | 0.84 | LMNA (0.42) | LMNATDP1KDM4EALDH1A1HTR2A | |
| SCHEMBL18493238 | 0.79 | TAAR1 (0.39) | LMNATDP1KDM4EALDH1A1HTR2A | |
| SCHEMBL30518068 | 0.79 | SLC6A2 (0.42) | LMNATDP1KDM4EALDH1A1HTR2A | |
| SCHEMBL986924 | 0.78 | HTR2A (0.41) | LMNATDP1ALDH1A1HTR2AHRH1 | |
| SCHEMBL8751571 | 0.76 | LMNA (0.47) | LMNATDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL7181278 | 0.76 | CYP3A4 (0.35) | LMNATDP1KDM4EALDH1A1HTR2A | |
| SCHEMBL689805 | 0.76 | ALDH1A1 (0.42) | LMNATDP1KDM4EALDH1A1HTR2A | |
| SCHEMBL12067933 | 0.76 | ALDH1A1 (0.42) | LMNATDP1KDM4EALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968735-B2 | Light-emitting biomarker | QUIDD (FR) | 2011-06-28 | — | — | US | claimed |
| US-20090041669-A1 | Light-Emitting Biomarker | QUIDD (FR) | 2009-02-12 | — | — | US | claimed |
| US-4891306-A | FLUOROPOLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 1990-01-02 | — | — | US | claimed |
| CN-114588270-A | Compositions comprising nanoparticles of taxanes and uses thereof | DFB索里亚有限责任公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-107076674-A | Analysis method using SERS and the composition for methods described | 庄信万丰股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| US-7968735-B2 | Light-emitting biomarker | QUIDD (FR) | 2011-06-28 | — | — | US | disclosed |
| US-20090041669-A1 | Light-Emitting Biomarker | QUIDD (FR) | 2009-02-12 | — | — | US | disclosed |
| WO-2008137773-A1 | COMPOSITION FOR IN SITU MANUFACTURE OF INSOLUBLE HYDROXIDE WHEN CLEANING HARD SURFACES AND FOR USE IN AUTOMATIC WAREWASHING MACHINES, AND METHODS FOR MANUFACTURING AND USING | ECOLAB INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| US-20080274932-A1 | COMPOSITION FOR IN SITU MANUFACTURE OF INSOLUBLE HYDROXIDE WHEN CLEANING HARD SURFACES AND FOR USE IN AUTOMATIC WAREWASHING MACHINES AND METHODS FOR MANUFACTURING AND USING | ECOLAB INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20060204687-A1 | Ink-jet recording sheet | KONICA MINOLTA PHOTO IMAGING, INC. (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1669209-A1 | Ink-jet recording sheet and producing method of the same | Konica Minolta Photo Imaging, Inc. (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-0016623-B1 | WATER-SOLUBLE POLYMERS CONTAINING QUATERNARY AMMONIUM GROUPS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE IN IMPROVING THE WET STRENGTH OF CELLULOSIC SUBSTRATES | MONSANTO COMPANY (US) | 1983-12-28 | — | — | EP | disclosed |
| US-4343730-A | WATER AND SEWAGE TREATMENT | PETROLITE CORPORATION (US) | 1982-08-10 | — | — | US | disclosed |
| US-4340692-A | CATIONIC THERMOSETTING RESINS | MONSANTO COMPANY (US) | 1982-07-20 | — | — | US | disclosed |
| US-4312969-A | REFLUXING LOW BOILING LIQUID TO DISSIPATE HEAT | PETROLITE CORPORATION (US) | 1982-01-26 | — | — | US | disclosed |
| US-4298639-A | WATER SOLUBLE, CATIONIC, THERMOSETTING, HAVING GLYCIDYL QUATERNARY AMMONIUM GROUPS FOR APPLICATION TO CELLULOSE SUBSTRATES | MONSANTO COMPANY (US) | 1981-11-03 | — | — | US | disclosed |
| US-4233417-A | EPICHLOROHYDRIN-TERTIARY AMINE CATIONIC SALT POLYMER IS AN ADDITIVE FOR CELLULOSIC SUBSTRATES | MONSANTO COMPANY (US) | 1980-11-11 | — | — | US | disclosed |
| EP-0016623-A1 | Water-soluble polymers containing quaternary ammonium groups, a process for their production and their use in improving the wet strength of cellulosic substrates | MONSANTO COMPANY (US) | 1980-10-01 | — | — | EP | disclosed |
| US-4035347-A | Method for the preparation of dried latex polymer from aqueous emulsion | NALCO CHEMICAL COMPANY (US) | 1977-07-12 | — | — | US | disclosed |
| US-4025712-A | HYDROLYZING THE EMULSIFIER | NALCO CHEMICAL COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090041669-A1 | Light-Emitting Biomarker | ALDH1A2, CYP19A1, GUSB | HTR2A 3483/4885HRH1 3865/4885SLC6A2 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.