SCHEMBL8752240

SCHEMBL8752240

C=CC(CN1CNc2c1nc(N)[nH]c2=O)OCP(=O)(O)O

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 18/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4713155 0.84 HPRT1 (0.76) HPRT1
Phosphoric Acid SCHEMBL15054256 0.83 HPRT1 (0.74) HPRT1
SCHEMBL84258 0.83 HPRT1 (1.00) HPRT1
SCHEMBL9189461 0.82 HPRT1 (1.00) HPRT1
SCHEMBL8896319 0.79 HPRT1 (0.68) HPRT1
SCHEMBL8896070 0.79 HPRT1 (0.74) HPRT1
SCHEMBL23223497 0.78 HPRT1 (0.69) HPRT1
SCHEMBL9055682 0.78 HPRT1 (0.81) HPRT1
SCHEMBL8752213 0.78 HPRT1 (0.57) HPRT1
SCHEMBL9054484 0.78 HPRT1 (0.71) HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630381-B1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES ACAD OF SCIENCE CZECH REPUBLIC (CZ) 1997-04-09 EP disclosed
EP-0630381-A4 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. 1995-01-04 EP disclosed
EP-0630381-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. ACAD OF SCIENCE CZECH REPUBLIC (CS) 1994-12-28 EP disclosed
WO-1993007157-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OFTHE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1993-04-15 WO disclosed