Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 15/20 | 0.81 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84258 | 0.90 | HPRT1 (1.00) | HPRT1FGFR1SLC22A6TYMPMEN1 | |
| SCHEMBL9417241 | 0.83 | HPRT1 (0.74) | HPRT1FGFR1SLC22A6TYMPMEN1 | |
| SCHEMBL8896070 | 0.83 | HPRT1 (0.74) | HPRT1FGFR1SLC22A6MEN1ALDH1A1 | |
| Phosphoric Acid SCHEMBL1664405 | 0.83 | HPRT1 (0.62) | HPRT1 | |
| SCHEMBL9189461 | 0.82 | HPRT1 (1.00) | HPRT1FGFR1SLC22A6TYMP | |
| SCHEMBL64568 | 0.81 | HPRT1 (1.00) | HPRT1TYMP | |
| SCHEMBL146837 | 0.80 | HPRT1 (0.58) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL4713155 | 0.80 | HPRT1 (0.76) | HPRT1TYMPCYP3A4 | |
| Phosphoric Acid SCHEMBL3497655 | 0.80 | HPRT1 (0.98) | HPRT1TYMP | |
| Phosphoric Acid SCHEMBL15054256 | 0.79 | HPRT1 (0.74) | HPRT1TYMPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269947-B2 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1996-10-16 | — | — | EP | claimed |
| EP-0269947-A1 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1988-06-08 | — | — | EP | claimed |