⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386798 | 0.76 | — | — | |
| SCHEMBL29236046 | 0.74 | — | — | |
| SCHEMBL3275918 | 0.74 | — | — | |
| SCHEMBL9957230 | 0.68 | TSHR (0.34) | — | |
| SCHEMBL28466983 | 0.67 | CHRM3 (0.35) | — | |
| SCHEMBL11315463 | 0.67 | NPC1 (0.33) | — | |
| SCHEMBL1835482 | 0.67 | — | — | |
| SCHEMBL27489842 | 0.63 | NPC1 (0.30) | — | |
| SCHEMBL28271970 | 0.63 | — | — | |
| SCHEMBL27447556 | 0.63 | TRPA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | MELINTA SUBSIDIARY CORP. (US) | 2024-06-04 | — | — | US | disclosed |
| EP-4356736-A2 | SYNTHESIS OF BORONATE SALTS | Melinta Therapeutics, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-3604316-B1 | SYNTHESIS OF BORONATE SALTS | MELINTA THERAPEUTICS INC (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20200308197-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2020-10-01 | — | — | US | disclosed |
| EP-3704130-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | Melinta Therapeutics, Inc. (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10669292-B2 | Synthesis of boronate salts and uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| EP-3604316-A1 | SYNTHESIS OF BORONATE SALTS | Rempex Pharmaceuticals, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| US-20200031851-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2020-01-30 | — | — | US | disclosed |
| US-10385074-B2 | Synthesis of boronate salts and uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2019-08-20 | — | — | US | disclosed |
| EP-3140310-B1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | REMPEX PHARMACEUTICALS INC (US) | 2019-08-07 | — | — | EP | disclosed |
| US-20190127396-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | CORTLAND CAPITAL MARKET SERVICES LLC, AS AGENT | 2019-05-02 | — | — | US | disclosed |
| EP-3140310-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | Rempex Pharmaceuticals, Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170057979-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2017-03-02 | — | — | US | disclosed |
| WO-2015171430-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2015-11-12 | — | — | WO | disclosed |
| US-20120095211-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |