Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28466983 | 0.84 | CHRM3 (0.35) | TSHRTHRBBLM | |
| SCHEMBL10398578 | 0.80 | ALDH1A1 (0.38) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL7716551 | 0.80 | TSHR (0.33) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL11312589 | 0.80 | TSHR (0.33) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL1236956 | 0.79 | TSHR (0.33) | TSHRMAPK1HSD17B10TDP1THRB | |
| Hydrochloric Acid SCHEMBL5502358 | 0.77 | THRB (0.34) | TSHRMAPK1HSD17B10TDP1THRB | |
| Hydrochloric Acid SCHEMBL17667153 | 0.77 | THRB (0.34) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL7799639 | 0.75 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL28274200 | 0.74 | — | — | |
| SCHEMBL8837708 | 0.73 | TSHR (0.36) | TSHRMAPK1HSD17B10TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2741731-A1 | ENCAPSULATES | The Procter and Gamble Company (US) | 2014-06-18 | — | — | EP | disclosed |
| WO-2013022949-A1 | ENCAPSULATES | THE PROCTER & GAMBLE COMPANY (US) | 2013-02-14 | — | — | WO | disclosed |
| WO-2012085864-A1 | ENCAPSULATES | PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA (CH) | 2012-06-28 | — | — | WO | disclosed |