Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6126856 | 1.00 | HPGDS (0.36) | HPGDSCYP2C9KCNH2GPR119PARP1 | |
| SCHEMBL15396052 | 1.00 | HPGDS (0.36) | HPGDSCYP2C9KCNH2GPR119PARP1 | |
| SCHEMBL6126858 | 1.00 | HPGDS (0.36) | HPGDSCYP2C9KCNH2GPR119PARP1 | |
| SCHEMBL12531099 | 0.88 | HPGDS (0.36) | HPGDSCYP2C9KCNH2GPR119PARP1 | |
| SCHEMBL1914159 | 0.87 | HPGDS (0.36) | HPGDSCYP2C9KCNH2GPR119PARP1 | |
| SCHEMBL15898208 | 0.87 | CFD (0.38) | HPGDSGPR119PARP1UCHL1HSD11B1 | |
| SCHEMBL14848753 | 0.87 | HPGDS (0.36) | HPGDSCYP2C9KCNH2GPR119PARP1 | |
| SCHEMBL1914160 | 0.87 | HPGDS (0.36) | HPGDSCYP2C9KCNH2GPR119PARP1 | |
| SCHEMBL15586266 | 0.87 | HPGDS (0.36) | HPGDSCYP2C9KCNH2GPR119PARP1 | |
| SCHEMBL903365 | 0.87 | CFD (0.38) | HPGDSGPR119PARP1UCHL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |