Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.46 |
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017255 | 1.00 | FAAH (0.46) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28599689 | 0.98 | FAAH (0.44) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28405424 | 0.89 | MAPT (0.39) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28339298 | 0.83 | MAPT (0.37) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL457604 | 0.79 | FAAH (0.48) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL5615079 | 0.79 | FAAH (0.48) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29047796 | 0.78 | FAAH (0.47) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28583564 | 0.76 | MAPT (0.51) | FAAHMEN1KMT2AMAPTMAPK1 | |
| Sulfuric Acid SCHEMBL29052908 | 0.74 | FAAH (0.43) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL5846747 | 0.74 | FAAH (0.43) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627311-A1 | COSMETIC COMPOSITION COMPRISING A PARTICULAR SILICON DERIVATIVE AND ONE OR MORE ACRYLIC THICKENING POLYMERS | L'Oréal (FR) | 2013-08-21 | — | — | EP | disclosed |
| US-20130164248-A1 | COSMETIC COMPOSITION COMPRISING A PARTICULAR SILICON DERIVATIVE AND ONE OR MORE ACRYLIC THICKENING POLYMERS | L'OREAL (FR) | 2013-06-27 | — | — | US | disclosed |
| WO-2012175677-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE PARTICULAR AMPHOTERIC POLYMER AND ONE PARTICULAR ANIONIC SURFACTANT | L'OREAL (FR) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012049145-A1 | COSMETIC COMPOSITION COMPRISING A PARTICULAR SILICON DERIVATIVE AND ONE OR MORE ACRYLIC THICKENING POLYMERS | L'OREAL (FR) | 2012-04-19 | — | — | WO | disclosed |
| WO-2012038534-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE CALCIUM SALT, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE CATIONIC SURFACTANT AND AT LEAST ONE THICKENER | L'OREAL (FR) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130164248-A1 | COSMETIC COMPOSITION COMPRISING A PARTICULAR SILICON DERIVATIVE AND ONE OR MORE ACRYLIC THICKENING POLYMERS | KRT18, OR10J3, OR51E2 | FAAH 2264/4885CES1 2896/4885CES2 2374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.