SCHEMBL457604

SCHEMBL457604

CCCCCCCCCCCCCCCCCC(=O)C(C)(NC(C)O)C(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 9/20 0.48
▸ CES1 P23141 5/20 0.48
▸ CES2 O00748 2/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ CYP1A2 P05177 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ MAPK1 P28482 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.44
▸ TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5615079 1.00 FAAH (0.48) FAAHCES1CES2MEN1KMT2A
Hydrochloric Acid SCHEMBL29047796 0.98 FAAH (0.47) FAAHCES1CES2MEN1KMT2A
Sulfuric Acid SCHEMBL29052908 0.94 FAAH (0.43) FAAHCES1CES2MEN1KMT2A
SCHEMBL5846747 0.94 FAAH (0.43) FAAHCES1CES2MEN1KMT2A
SCHEMBL26638038 0.88 FAAH (0.39) FAAHCES1CES2MEN1KMT2A
SCHEMBL28363752 0.88 FAAH (0.39) FAAHCES1CES2MEN1KMT2A
SCHEMBL28988025 0.82 FAAH (0.47) FAAHCES1MEN1KMT2ACYP1A2
SCHEMBL29174036 0.81 FAAH (0.47) FAAHCES1CES2MEN1KMT2A
SCHEMBL115277 0.81 FAAH (0.47) FAAHCES1CES2MEN1KMT2A
SCHEMBL9017255 0.79 FAAH (0.46) FAAHCES1CES2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2677990-B1 COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULFIDE/THIOL FUNCTION, A SPARINGLY OR NON-ETHOXYLATED FATTY ALCOHOL, A CATIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT OREAL (FR) 2019-05-15 — — EP claimed
EP-3207918-A1 USE OF A COSMETIC COMPOSITION CONTAINING A VOLATILE LINEAR ALKANE AND A NON-IONIC ASSOCIATIVE POLYMER FOR CONDITIONING HAIR L'OREAL (FR) 2017-08-23 — — EP disclosed
EP-2338469-B1 Use of a cosmetic composition containing a linear volatile alcane and an associative non-ionic polymer for conditioning the hair L'ORÉAL (FR) 2017-04-12 — — EP disclosed
EP-2322135-B1 Cosmetic composition including a structuring agent, an absorbent agent and a surfactant for application to keratin materials ORÉAL L (FR) 2016-05-11 — — EP disclosed
US-20130302266-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC POLYMER AND AT LEAST TWO CATIONIC SURFACTANTS L'OREAL (FR) 2013-11-14 — — US disclosed
EP-2613761-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC POLYMER AND AT LEAST TWO CATIONIC SURFACTANTS L'Oréal (FR) 2013-07-17 — — EP disclosed
WO-2012120114-A1 METHOD FOR THE COSMETIC TREATMENT OF HUMAN PERSPIRATION COMPRISING THE APPLICATION OF A SOLUBILIZABLE ANTIPERSPIRANT POLYMER FILM L'OREAL (FR) 2012-09-13 — — WO disclosed
EP-2322136-B1 Cosmetic hair-conditioner composition containing a mixture of hollow particles, starch and a cationic surfactant OREAL (FR) 2012-07-04 — — EP disclosed
WO-2012032055-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC POLYMER AND AT LEAST TWO CATIONIC SURFACTANTS L'OREAL (FR) 2012-03-15 — — WO disclosed
US-20110168200-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE TYPE OF HOLLOW PARTICLE, AT LEAST ONE STARCH AND AT LEAST ONE CATIONIC SURFACTANT L'OREAL S.A (FR) 2011-07-14 — — US disclosed
EP-2338468-A1 Cosmetic composition comprising at least one volatile linear alkane, at least one cationic surfactant whereby the two components are in a specific ratio L'Oréal (FR) 2011-06-29 — — EP disclosed
EP-2338469-A1 Use of a cosmetic composition containing a linear volatile alcane and an associative non-ionic polymer for conditioning the hair L'Oréal (FR) 2011-06-29 — — EP disclosed
EP-2322135-A1 Cosmetic composition including a structuring agent, an absorbent agent and a surfactant for application to keratin materials L'Oréal (FR) 2011-05-18 — — EP disclosed
EP-2322136-A1 Cosmetic hair-conditioner composition containing a mixture of hollow particles, starch and a cationic surfactant L'Oréal (FR) 2011-05-18 — — EP disclosed
US-20090123397-A1 Microbiocidal compositions THOR SPECIALITIES (UK) LIMITED (GB) 2009-05-14 — — US disclosed
EP-2000122-A2 Microbiocidal composition Thor Specialities (UK) Lmited (GB) 2008-12-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130302266-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC POLYMER AND AT LEAST TWO CATIONIC SURFACTANTS DSG1, ALG1, PARG FAAH 2926/4885CES1 3089/4885CES2 1652/4885
US-20110168200-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE TYPE OF HOLLOW PARTICLE, AT LEAST ONE STARCH AND AT LEAST ONE CATIONIC SURFACTANT SGMS1, LIPA, SGMS2 FAAH 1113/4885CES1 534/4885CES2 829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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