Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14687934 | 0.89 | ARG1 (0.36) | ARG1ALOX15KDM4EPKMALDH1A1 | |
| SCHEMBL3431008 | 0.85 | CHRNB2 (0.33) | — | |
| SCHEMBL2118382 | 0.85 | CHRNB2 (0.33) | — | |
| SCHEMBL2119632 | 0.85 | CHRNB2 (0.33) | — | |
| SCHEMBL2587876 | 0.79 | CHRNB2 (0.32) | — | |
| SCHEMBL27156628 | 0.73 | GAA (0.32) | ALOX15ALDH1A1CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL19064830 | 0.70 | ARG1 (0.43) | ARG1ALOX15KDM4EPKMALDH1A1 | |
| SCHEMBL29587084 | 0.70 | — | — | |
| SCHEMBL31298422 | 0.69 | CYP2D6 (0.39) | ALOX15CYP1A2CYP2C19 | |
| SCHEMBL17959546 | 0.69 | CYP2D6 (0.39) | ALOX15CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |