Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22289183 | 0.84 | CSNK1E (0.45) | CYP2C19CYP1A2CYP2C9TP53SMN1; SMN2 | |
| SCHEMBL28920634 | 0.84 | CSNK1E (0.45) | CYP2C19CYP1A2CYP2C9TP53SMN1; SMN2 | |
| SCHEMBL27671625 | 0.83 | CYP2C19 (0.48) | CYP2C19CYP1A2CYP2C9SLC6A2TAAR1 | |
| SCHEMBL9545396 | 0.83 | CYP2C19 (0.48) | CYP2C19CYP1A2CYP2C9SLC6A2TAAR1 | |
| SCHEMBL19030861 | 0.82 | CYP1A2 (0.52) | CYP2C19CYP1A2CYP2C9SLC6A2TAAR1 | |
| SCHEMBL10476772 | 0.81 | CYP1A2 (0.61) | CYP2C19CYP1A2CYP2C9SLC6A2TAAR1 | |
| SCHEMBL15255042 | 0.81 | SLC6A2 (0.48) | CYP2C19CYP1A2CYP2C9SLC6A2TAAR1 | |
| SCHEMBL8643657 | 0.79 | SLC6A2 (0.52) | CYP2C19CYP1A2CYP2C9SLC6A2TAAR1 | |
| SCHEMBL3401044 | 0.78 | CYP1A2 (0.70) | CYP2C19CYP1A2CYP2C9SLC6A2TAAR1 | |
| SCHEMBL2579939 | 0.77 | CYP1A2 (0.52) | CYP2C19CYP1A2CYP2C9SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359306-B2 | Process for preparing pan-CDK inhibitors of the formula (I), and intermediates in the preparation | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-07 | — | — | US | disclosed |
| US-20150118480-A1 | LOW DENSITY EPOXY COMPOSITION WITH LOW WATER UPTAKE | 3M INNOVATIVE PROPERTIES COMPANY | 2015-04-30 | — | — | US | disclosed |
| EP-2653486-B1 | Low density epoxy composition with low water uptake | 3M INNOVATIVE PROPERTIES CO (US) | 2014-12-03 | — | — | EP | disclosed |
| WO-2013158517-A1 | LOW DENSITY EPOXY COMPOSITION WITH LOW WATER UPTAKE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-10-24 | — | — | WO | disclosed |
| EP-2653486-A1 | Low density epoxy composition with low water uptake | 3M Innovative Properties Company (US) | 2013-10-23 | — | — | EP | disclosed |
| US-20130245261-A1 | PROCESS FOR PREPARING PAN-CDK INHIBITORS OF THE FORMULA (I), AND INTERMEDIATES IN THE PREPARATION | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-19 | — | — | US | disclosed |
| EP-2619186-A1 | PROCESS FOR PREPARING PAN-CDK INHIBITORS OF THE FORMULA (I), AND INTERMEDIATES IN THE PREPARATION | Bayer Pharma Aktiengesellschaft (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038411-A1 | PROCESS FOR PREPARING PAN-CDK INHIBITORS OF THE FORMULA (I), AND INTERMEDIATES IN THE PREPARATION | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245261-A1 | PROCESS FOR PREPARING PAN-CDK INHIBITORS OF THE FORMULA (I), AND INTERMEDIATES IN THE PREPARATION | CDK1, CDK9, CDK6 | CYP2C19 708/4885CYP1A2 1630/4885CYP2C9 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.