Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8755145

C1=CC([Ti](C2C=Cc3ccccc32)=[Si](c2ccccc2)c2ccccc2)c2ccccc21.[Cl-].[H-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.34
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8754993 0.98 HTR2A (0.35) HTR2AHTR6
Hydrochloric Acid SCHEMBL7644431 0.95 HTR2A (0.35) HTR2AHTR6
Hydrochloric Acid SCHEMBL8382418 0.83 KDM4E (0.31) HTR2A
Hydrochloric Acid SCHEMBL8754924 0.79 HTR2A (0.36) HTR2AHTR6
Hydrochloric Acid SCHEMBL4461326 0.79 HTR2A (0.33) HTR2AHTR6
SCHEMBL8755273 0.77 HTR2A (0.37) HTR2AHTR6
SCHEMBL2534257 0.75 HTR2A (0.38) HTR2AHTR6
Hydrochloric Acid SCHEMBL7643969 0.74 HTR2A (0.37) HTR2AHTR6
Hydrochloric Acid SCHEMBL8384344 0.71
SCHEMBL7029033 0.70 SIGMAR1 (0.38) HTR2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed