⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644031 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL14605027 | 0.77 | ALDH1A1 (0.42) | — | |
| SCHEMBL8903927 | 0.74 | — | — | |
| SCHEMBL3500777 | 0.74 | CRBN (0.36) | — | |
| SCHEMBL9257808 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL5035422 | 0.70 | — | — | |
| SCHEMBL103453 | 0.70 | — | — | |
| SCHEMBL5024897 | 0.70 | — | — | |
| SCHEMBL56768 | 0.70 | TSHR (0.36) | — | |
| SCHEMBL102982 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1827 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115811990-A | Novel nucleolin binding peptides and uses thereof | 安尼根有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-109071622-B | Peptides with anticancer activity | IDP研发制药有限公司（ES） | 2023-01-13 | — | — | CN | claimed |
| CN-111467500-B | Low-oxygen dual-targeting AGT inhibitor conjugate and preparation method and application thereof | 北京工业大学 | 2022-08-09 | — | — | CN | claimed |
| CN-113717174-B | Tumor targeting drug resistant O6-thienylmethylguanine-indoloquinone-chloroethylnitrosourea combined molecule and preparation method thereof | 北京工业大学 | 2022-07-12 | — | — | CN | claimed |
| CN-114280053-A | Classification of maturity of stained reticulocytes using light microscopy | 西门子医疗有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-110591076-B | Low-oxygen targeting AGT inhibitor conjugate and preparation method and application thereof | 北京工业大学 | 2022-02-11 | — | — | CN | claimed |
| CN-113717174-A | Tumor targeting drug resistant O6-thienylmethylguanine-indoloquinone-chloroethylnitrosourea combined molecule and preparation method thereof | 北京工业大学 | 2021-11-30 | — | — | CN | claimed |
| EP-3430031-B1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP DISCOVERY PHARMA S L (ES) | 2021-10-20 | — | — | EP | claimed |
| EP-3862354-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2021-08-11 | — | — | EP | claimed |
| EP-2824105-B1 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2021-03-31 | — | — | EP | claimed |
| US-20020156033-A1 | Immunostimulatory nucleic acids and cancer medicament combination therapy for the treatment of cancer | COLEY PHARMACEUTICAL GROUP, INC. | 2002-10-24 | — | — | US | claimed |
| WO-2002023185-A2 | DEVICES AND METHODS FOR DIRECT ELECTRONIC READOUT OF BIOMOLECULAR INTERACTIONS | ENGENEOS, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2001097843-A2 | METHODS FOR ENHANCING ANTIBODY-INDUCED CELL LYSIS AND TREATING CANCER | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2001-12-27 | — | — | WO | claimed |
| WO-1999025386-A1 | delta-O6-METHYLGUANINE-DNA METHYLTRANSFERASE GENE TRANSFER FOR O6-BENZYLGUANINE AND (N,N'-BIS(2-CHLOROETHYL)-N-NITROSOUREA) RESISTANCE | CASE WESTERN RESERVE UNIVERSITY (US) | 1999-05-27 | — | — | WO | claimed |
| EP-0758249-A1 | PROGRAMMABLE GENOTOXIC AGENTS AND USES THEREFOR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1997-02-19 | — | — | EP | claimed |
| EP-0523100-B1 | O6 -BENZYLATED GUANINE, GUANOSINE AND 2'-DEOXYGUANOSINE COMPOUNDS POSSESSING O6 -ALKYLGUANINE-DNA ALKYLTRANSFERASE DEPLETING ACTIVITY | US HEALTH (US) | 1996-08-28 | — | — | EP | claimed |
| WO-1995030442-A1 | PROGRAMMABLE GENOTOXIC AGENTS AND USES THEREFOR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1995-11-16 | — | — | WO | claimed |
| EP-0668782-A1 | COMBINATION OF ANTINEOPLASTIC AGENT AND ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1995-08-30 | — | — | EP | claimed |
| US-5358952-A | Anticarcinogenic agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-10-25 | — | — | US | claimed |
| WO-1994008625-A1 | COMBINATION OF ANTINEOPLASTIC AGENT AND ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1994-04-28 | — | — | WO | claimed |