SCHEMBL56768

SCHEMBL56768

CCN(N=O)C(=O)N(Cl)Cl

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
MEN1 O00255 1/20 0.31
ABCB11 O95342 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GSR P00390 1/20 0.31
HTT P42858 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
KMT2A Q03164 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103453 0.72
SCHEMBL5024897 0.72
SCHEMBL8903927 0.71
SCHEMBL846155 0.70
SCHEMBL102982 0.70
Ethyl Nitrosourea SCHEMBL77485 0.70
SCHEMBL87564 0.70
SCHEMBL4460224 0.67 ALDH1A1 (0.36) TSHRMEN1ABCB11ALDH1A1GSR
SCHEMBL103666 0.67 CES2 (0.38) TSHRMEN1ABCB11ALDH1A1GSR
SCHEMBL103983 0.67 TSHR (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3395 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028400-A1 ANTI-ROR1 ANTIBODY AND USE THEREOF AIMED BIO INC (KR) 2026-01-29 US claimed
US-20250270320-A1 ANTI-PD-1 ANTIBODY AND USES THEREOF EUTILEX CO., LTD. (KR) 2025-08-28 US claimed
EP-4563597-A1 ANTI-ROR1 ANTIBODY AND USE THEREOF AIMED BIO INC. (KR) 2025-06-04 EP claimed
US-20250171745-A1 ADENOVIRUS EXPRESSING IMMUNE CELL STIMULATORY RECEPTOR AGONIST(S) DNATRIX INC (US) 2025-05-29 US claimed
US-20250032629-A1 NOVEL NUCLEOLIN-BINDING PEPTIDE AND USE THEREOF ANYGEN CO., LTD. (KR) 2025-01-30 US claimed
CN-114716548-B Anti-FGFR 3 antibodies and uses thereof (株)爱恩德生物 2024-11-05 CN claimed
US-20240216492-A1 USE OF ONCOLYTIC ADENOVIRUS FOR THE TREATMENT OF PEDIATRIC BRAIN CANCER CV BIOMANUFACTURING, LLC 2024-07-04 US claimed
EP-4329878-A1 USE OF ONCOLYTIC ADENOVIRUS FOR THE TREATMENT OF PEDIATRIC BRAIN CANCER Dnatrix, Inc. (US) 2024-03-06 EP claimed
WO-2024025343-A1 ANTI-ROR1 ANTIBODY AND USE THEREOF (주)에임드바이오 2024-02-01 WO claimed
EP-4276112-A1 ANTI-FGFR3 ANTIBODY AND USE THEREOF AIMED BIO INC. (KR) 2023-11-15 EP claimed
WO-2007012133-A1 THERAPEUTIC PROTOCOLS USING HYALURONAN ALCHEMIA ONCOLOGY PTY LIMITED (AU) 2007-02-01 WO claimed
US-20050215498-A1 Method for the protection of endothelial and epithclial cells during chemotherapy KLINIKUM DER UNIVERSITAET REGENSBURG (DE) 2005-09-29 US claimed
US-6932777-B2 Prophylactic and therapeutic treatment of the ductal epithelium of a mammary gland for cancer JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) 2005-08-23 US claimed
US-20040072786-A1 Antisense oligonucleotide inhibition of ras MONIA BRETT P (US) 2004-04-15 US claimed
US-6656918-B2 Contacting the ductal epithelium of the exocrine gland with epithelium destroying agents such as ethanol and vaccinia virus JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE 2003-12-02 US claimed
EP-0909184-B1 TARGETED DRUG DELIVERY USING SULFONAMIDE DERIVATIVES UPJOHN CO (US) 2003-09-17 EP claimed
US-20030013670-A1 Antisense oligonucleotide inhibition of ras ISIS PHARMACEUTICALS, INC. 2003-01-16 US claimed
EP-0668782-B1 COMBINATION OF ANTINEOPLASTIC AGENT AND ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER UNIV TEMPLE (US) 2001-04-11 EP claimed
EP-0668782-A1 COMBINATION OF ANTINEOPLASTIC AGENT AND ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1995-08-30 EP claimed
WO-1994008625-A1 COMBINATION OF ANTINEOPLASTIC AGENT AND ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1994-04-28 WO claimed