SCHEMBL8756499

SCHEMBL8756499

CCCCCCCCCCCCN=Cc1ccc(O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.73
KMT2A Q03164 2/20 0.73
LMNA P02545 3/20 0.52
MAPT P10636 3/20 0.52
MEN1 O00255 1/20 0.52
MAPK1 P28482 1/20 0.52
TAAR1 Q96RJ0 1/20 0.51
CA2 P00918 4/20 0.50
MIF P14174 1/20 0.49
ESR1 P03372 2/20 0.47
ADRA2A P08913 2/20 0.47
ADORA3 P0DMS8 2/20 0.47
TACR2 P21452 2/20 0.47
SLC6A2 P23975 2/20 0.47
SLC6A4 P31645 2/20 0.47
SLC6A3 Q01959 2/20 0.47
KDM4E B2RXH2 2/20 0.47
SHBG P04278 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8756569 1.00 ALDH1A1 (0.73) ALDH1A1KMT2ALMNAMAPTMEN1
SCHEMBL8755991 1.00 ALDH1A1 (0.73) ALDH1A1KMT2ALMNAMAPTMEN1
SCHEMBL8756576 1.00 ALDH1A1 (0.73) ALDH1A1KMT2ALMNAMAPTMEN1
SCHEMBL8755989 1.00 ALDH1A1 (0.73) ALDH1A1KMT2ALMNAMAPTMEN1
SCHEMBL8756493 1.00 ALDH1A1 (0.73) ALDH1A1KMT2ALMNAMAPTMEN1
SCHEMBL474264 0.93 ALDH1A1 (0.79) ALDH1A1KMT2ALMNAMAPTMEN1
SCHEMBL10251040 0.93 ALDH1A1 (0.79) ALDH1A1KMT2ALMNAMAPTMEN1
SCHEMBL9810590 0.91 ALDH1A1 (0.57) ALDH1A1KMT2ALMNAMAPTMEN1
SCHEMBL9810599 0.91 ALDH1A1 (0.57) ALDH1A1KMT2ALMNAMAPTMEN1
SCHEMBL20417359 0.87 ALDH1A1 (0.57) ALDH1A1KMT2ALMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574879-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1997-05-02 EP disclosed
US-5395815-A Phenolic compound electron acceptor; images; contrast; stability MITSUBISHI PAPER MILLS LIMITED (JP) 1995-03-07 US disclosed
EP-0574879-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1993-12-22 EP disclosed