Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | MIF | P14174 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10251040 | 1.00 | ALDH1A1 (0.79) | ALDH1A1KMT2ATAAR1CA2MIF | |
| SCHEMBL8756499 | 0.93 | ALDH1A1 (0.73) | ALDH1A1KMT2ATAAR1CA2MIF | |
| SCHEMBL8756576 | 0.93 | ALDH1A1 (0.73) | ALDH1A1KMT2ATAAR1CA2MIF | |
| SCHEMBL8755989 | 0.93 | ALDH1A1 (0.73) | ALDH1A1KMT2ATAAR1CA2MIF | |
| SCHEMBL8756493 | 0.93 | ALDH1A1 (0.73) | ALDH1A1KMT2ATAAR1CA2MIF | |
| SCHEMBL8756569 | 0.93 | ALDH1A1 (0.73) | ALDH1A1KMT2ATAAR1CA2MIF | |
| SCHEMBL8755991 | 0.93 | ALDH1A1 (0.73) | ALDH1A1KMT2ATAAR1CA2MIF | |
| SCHEMBL5680683 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KMT2ATAAR1CA2MIF | |
| SCHEMBL5680680 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KMT2ATAAR1CA2MIF | |
| SCHEMBL12389205 | 0.88 | ALDH1A1 (1.00) | ALDH1A1KMT2ATAAR1CA2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2112206-B1 | Polymer Composition | ROHM & HAAS (US) | 2016-06-29 | — | — | EP | disclosed |
| EP-2166043-B1 | Thickener composition and method for thickening aqueous systems | ROHM & HAAS (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-2166044-B1 | Thickened compositions and method for thickening aqueous polymer compositions | ROHM & HAAS (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20110281980-A1 | Thickener composition and method for thickening aqueous systems | BOBSEIN BARRETT RICHARD (US) | 2011-11-17 | — | — | US | disclosed |
| US-8034869-B2 | Thickened compositions and method for thickening aqueous polymer compositions | ROHM AND HAAS COMPANY (US) | 2011-10-11 | — | — | US | disclosed |
| US-7985795-B2 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY (US) | 2011-07-26 | — | — | US | disclosed |
| EP-1972665-B1 | Thickener composition and method for thickening aqueous systems | ROHM & HAAS (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20100286434-A1 | Ethylenically unsaturated monomers for thickener compositions | BOBSEIN BARRETT RICHARD | 2010-11-11 | — | — | US | disclosed |
| US-20100261813-A1 | Thickener composition and method for thickening aqueous systems | BOBSEIN BARRETT RICHARD | 2010-10-14 | — | — | US | disclosed |
| US-20100227953-A1 | Thickened compositions and method for thickening aqueous polymer compositions | ROHM AND HAAS COMPANY | 2010-09-09 | — | — | US | disclosed |
| US-7741402-B2 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY (US) | 2010-06-22 | — | — | US | disclosed |
| US-20100076145-A1 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY | 2010-03-25 | — | — | US | disclosed |
| EP-2166044-A1 | Thickened compositions and method for thickening aqueous polymer compositions | Rohm and Haas Company (US) | 2010-03-24 | — | — | EP | disclosed |
| EP-2166043-A2 | Thickener composition and method for thickening aqueous systems | Rohm and Haas Company (US) | 2010-03-24 | — | — | EP | disclosed |
| EP-2112206-A1 | Polymer Composition | Rohm and Haas Company (US) | 2009-10-28 | — | — | EP | disclosed |
| US-20080234411-A1 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY | 2008-09-25 | — | — | US | disclosed |
| EP-1972665-A2 | Thickener composition and method for thickening aqueous systems | Rohm and Haas Company (US) | 2008-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286434-A1 | Ethylenically unsaturated monomers for thickener compositions | ELOVL1, ELOVL6, ELOVL5 | ALDH1A1 2760/4885KMT2A 3275/4885TAAR1 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.