Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | HTR2C | P28335 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653659 | 1.00 | APP (0.62) | APPHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL8756981 | 0.86 | APP (0.62) | APPHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL8756992 | 0.86 | APP (0.62) | APPHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL8756987 | 0.86 | APP (0.62) | APPHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL6659156 | 0.84 | EGFR (0.56) | APPHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL6659147 | 0.84 | EGFR (0.56) | APPHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL5755690 | 0.84 | EGFR (0.64) | HTR1AHTR2CHTR2ASLC6A4HTR7 | |
| SCHEMBL19358993 | 0.83 | APP (0.64) | APPHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL19369311 | 0.83 | APP (0.64) | APPHTR1AHTR2CHTR2ASLC6A4 | |
| Feruloylhexylamide SCHEMBL14638587 | 0.79 | TYR (0.88) | APPHTR1AHTR2CHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254241-A1 | Enzyme inhibitor; cognition activators | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1431280-A1 | ARYL SULFAMATE DERIVATIVES | Kyowa Hakko Kogyo Co., Ltd (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254241-A1 | Enzyme inhibitor; cognition activators | SULT1A1, STS, CYP26A1 | APP 2002/4885HTR1A 140/4885HTR2C 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.