Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758116 | 0.82 | KDM4E (0.47) | MAOBFFAR1FFAR4 | |
| SCHEMBL8727296 | 0.80 | SLC6A4 (0.44) | MAOB | |
| SCHEMBL8727305 | 0.80 | SLC6A4 (0.44) | MAOB | |
| SCHEMBL8634988 | 0.80 | MAOB (0.45) | MAOBFFAR1FFAR4 | |
| SCHEMBL8636622 | 0.77 | KDM4E (0.49) | MAOB | |
| SCHEMBL8757963 | 0.77 | MAOB (0.59) | MAOB | |
| SCHEMBL8587673 | 0.76 | MAOB (0.61) | MAOBFFAR1FFAR4 | |
| Hydrochloric Acid SCHEMBL6157166 | 0.75 | MAOB (0.63) | MAOBFFAR1FFAR4 | |
| Hydrochloric Acid SCHEMBL27990941 | 0.74 | MAOB (0.70) | MAOB | |
| SCHEMBL8588987 | 0.73 | MAOB (0.57) | MAOBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772585-A1 | ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF | SMITHKLINE BEECHAM PLC (GB) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996004233-A1 | ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF | SMITHKLINE BEECHAM PLC (GB) | 1996-02-15 | — | — | WO | disclosed |