Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4002659 | 0.99 | MAOB (0.59) | MAOBPOLBMAPTSMN1; SMN2LMNA | |
| SCHEMBL3997587 | 0.88 | FFAR1 (0.50) | POLBMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5989500 | 0.86 | NPC1 (0.56) | POLBMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3997793 | 0.86 | LTA4H (0.56) | POLBMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9843420 | 0.86 | FFAR1 (0.64) | FFAR1FFAR4 | |
| SCHEMBL8587673 | 0.85 | MAOB (0.61) | MAOBFFAR1FFAR4SCN3A | |
| SCHEMBL3995121 | 0.85 | SLC6A5 (0.48) | MAOBPOLBMAPTSMN1; SMN2LMNA | |
| SCHEMBL13869734 | 0.85 | FFAR1 (0.52) | POLBMAPTSMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6157166 | 0.84 | MAOB (0.63) | MAOBFFAR1FFAR4 | |
| SCHEMBL3998062 | 0.84 | FFAR1 (0.52) | MAOBSMN1; SMN2LMNAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037056-A1 | PHENOXYPROPANOLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1998-08-27 | — | — | WO | disclosed |