Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727305 | 1.00 | SLC6A4 (0.44) | SLC6A4MAOBTAAR1SLC6A2SCN9A | |
| SCHEMBL8757973 | 0.80 | MAOB (0.59) | MAOB | |
| SCHEMBL8634988 | 0.79 | MAOB (0.45) | MAOBMAOA | |
| SCHEMBL8758116 | 0.79 | KDM4E (0.47) | SLC6A4MAOBSLC6A2MAOASLC6A3 | |
| SCHEMBL8732240 | 0.79 | SLC6A4 (0.49) | SLC6A4MAOBTAAR1SLC6A2LTA4H | |
| SCHEMBL8732948 | 0.78 | PTPN1 (0.48) | — | |
| SCHEMBL8758553 | 0.74 | SLC6A4 (0.44) | SLC6A4TAAR1SLC6A2MAOASLC6A3 | |
| SCHEMBL2750285 | 0.74 | LTA4H (0.67) | SLC6A4MAOBTAAR1SLC6A2LTA4H | |
| SCHEMBL12532788 | 0.74 | LTA4H (0.67) | SLC6A4MAOBTAAR1SLC6A2LTA4H | |
| SCHEMBL2750286 | 0.74 | LTA4H (0.67) | SLC6A4MAOBTAAR1SLC6A2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |
| EP-0772585-A1 | ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF | SMITHKLINE BEECHAM PLC (GB) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996004233-A1 | ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF | SMITHKLINE BEECHAM PLC (GB) | 1996-02-15 | — | — | WO | disclosed |