Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28268916 | 0.79 | TAAR1 (0.54) | HTR6HTR2AHRH1POLBKMT2A | |
| SCHEMBL8758329 | 0.79 | HTR2A (0.53) | HTR6HTR2AHRH1POLBKMT2A | |
| SCHEMBL28811759 | 0.79 | HTR6 (0.59) | HTR6HTR2AHRH1POLBSCN9A | |
| SCHEMBL9502361 | 0.79 | CYP19A1 (0.57) | HTR6HTR2APOLBKMT2A | |
| SCHEMBL4731450 | 0.77 | POLB (0.68) | HTR6HTR2AHRH1POLBKMT2A | |
| SCHEMBL31595698 | 0.77 | POLB (0.68) | HTR6HTR2AHRH1POLBKMT2A | |
| SCHEMBL4535061 | 0.76 | HTR2A (0.65) | HTR6HTR2AHRH1KMT2ASCN9A | |
| SCHEMBL8758275 | 0.76 | HTR6 (0.67) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL7674266 | 0.76 | POLB (0.67) | HTR6HTR2AHRH1POLBKMT2A | |
| SCHEMBL3842121 | 0.75 | TAAR1 (0.54) | HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623138-B1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UNION PHARMA SCIENT APPL (FR) | 1997-05-21 | — | — | EP | disclosed |
| US-5480983-A | ANALGESICS, HYPOTENSIVE AGENTS | LABORATOIRES UPSA (FR) | 1996-01-02 | — | — | US | disclosed |
| EP-0623138-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | UNION PHARMA SCIENT APPL (FR) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014102-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRES UPSA (FR) | 1993-07-22 | — | — | WO | disclosed |