Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752748 | 0.87 | HTR2A (0.51) | CYP19A1TAAR1MAPTHTR2AHTR6 | |
| SCHEMBL31595698 | 0.83 | POLB (0.68) | CYP19A1HTR2AHTR6POLBALDH1A1 | |
| SCHEMBL4731450 | 0.83 | POLB (0.68) | CYP19A1HTR2AHTR6POLBALDH1A1 | |
| SCHEMBL6706751 | 0.83 | CYP19A1 (0.65) | CYP19A1GAAGFERMAPTTP53 | |
| SCHEMBL28811759 | 0.82 | HTR6 (0.59) | CYP19A1TAAR1HTR2AHTR6POLB | |
| SCHEMBL28268916 | 0.82 | TAAR1 (0.54) | CYP19A1TAAR1HTR2AHTR6POLB | |
| SCHEMBL8758329 | 0.82 | HTR2A (0.53) | CYP19A1GAAMAPTTP53HTR2A | |
| SCHEMBL7753094 | 0.82 | HTR6 (0.69) | CYP19A1MAPTHTR2AHTR6POLB | |
| Hydrochloric Acid SCHEMBL7674266 | 0.82 | POLB (0.67) | CYP19A1HTR2AHTR6POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8986547 | 0.81 | HTR6 (0.67) | CYP19A1HTR2AHTR6POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229505-A | CNS and cardiovascular effects | LABORATOIRES UPSA (FR) | 1993-07-20 | — | — | US | disclosed |