Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603905 | 1.00 | PARP1 (0.61) | PARP1GAAALDH1A1PKML3MBTL1 | |
| SCHEMBL1091563 | 0.87 | PDK1 (0.66) | PARP1GAAALDH1A1PKML3MBTL1 | |
| SCHEMBL6953865 | 0.87 | PARP1 (0.61) | PARP1GAAALDH1A1PKML3MBTL1 | |
| SCHEMBL10632442 | 0.87 | PDK1 (0.50) | PARP1ALDH1A1PDK1LMNAMAPT | |
| SCHEMBL1251308 | 0.87 | CASP6 (0.64) | PDK1LMNATSHRCASP6 | |
| SCHEMBL9197453 | 0.87 | PARP1 (0.57) | PARP1GAAALDH1A1PKML3MBTL1 | |
| SCHEMBL27639792 | 0.85 | PDK1 (0.52) | PARP1ALDH1A1PDK1LMNATSHR | |
| SCHEMBL7510384 | 0.85 | PARP1 (0.59) | PARP1GAAALDH1A1PKML3MBTL1 | |
| SCHEMBL6112769 | 0.81 | PARP1 (0.55) | PARP1GAAALDH1A1PKML3MBTL1 | |
| Sulfuric Acid SCHEMBL6393967 | 0.81 | CASP6 (0.57) | LMNATSHRPOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101721-A | Solid phase synthesis of protected peptides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1978-07-18 | — | — | US | claimed |
| EP-0548217-B1 | PROCESS FOR THE PREPARATION OF C-TERMINALLY AMIDATED PEPTIDES | BUCHARDT OLE (DK) | 1997-04-09 | — | — | EP | disclosed |
| US-5580751-A | REACTING A PEPTIDE WITH A NUCLEOPHILIC AMINE IN THE PRESENCE OF TRYPSIN OR A CARBOXYPEPIDASE; NONENZYMATICALLY CLEAVING TO FORM THE PRODUCT | CARLSBERG A/S (DK) | 1996-12-03 | — | — | US | disclosed |
| EP-0548217-A1 | PROCESS FOR THE PREPARATION OF C-TERMINALLY AMIDATED PEPTIDES. | BUCHARDT OLE (DK) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005271-A1 | PROCESS FOR THE PREPARATION OF C-TERMINALLY AMIDATED PEPTIDES | BUCHARDT OLE (DK) | 1992-04-02 | — | — | WO | disclosed |
| US-4189605-A | 3-Nitro-4-bromomethyl benzoic acid | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-02-19 | — | — | US | disclosed |
| US-4101721-A | Solid phase synthesis of protected peptides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4062746-A | Solid phase synthesis of protected peptides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1977-12-13 | — | — | US | disclosed |