SCHEMBL8758480

SCHEMBL8758480

C=Cc1ccccc1COCCC[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TEAD3 Q99594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193381 0.88 ALDH1A1 (0.36) ALDH1A1TEAD3
SCHEMBL9193908 0.88 ALDH1A1 (0.36) ALDH1A1TEAD3
SCHEMBL7768663 0.83 ALDH1A1 (0.33) ALDH1A1TEAD3
SCHEMBL7768640 0.83 ALDH1A1 (0.33) ALDH1A1TEAD3
SCHEMBL759640 0.83 ALDH1A1 (0.40) ALDH1A1
SCHEMBL9544583 0.83 L3MBTL1 (0.35) ALDH1A1TEAD3
SCHEMBL20241507 0.82 ALDH1A1 (0.38) ALDH1A1
SCHEMBL7768631 0.82 GBA1 (0.33) ALDH1A1TEAD3
SCHEMBL3371484 0.82 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3959527 0.82 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0494549-B1 3-(Vinylbenzyloxy)propylsilane compounds and their preparation SHINETSU CHEMICAL CO (JP) 1997-05-28 EP claimed
US-5326895-A 3-(vinylbenzyloxy)propylsilane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-07-05 US claimed
EP-0494549-A1 3-(Vinylbenzyloxy)propylsilane compounds, their preparation and polymers thereof Shin-Etsu Chemical Co., Ltd. (JP) 1992-07-15 EP claimed
EP-0494549-B1 3-(Vinylbenzyloxy)propylsilane compounds and their preparation SHINETSU CHEMICAL CO (JP) 1997-05-28 EP disclosed
EP-0494549-B1 3-(Vinylbenzyloxy)propylsilane compounds and their preparation SHINETSU CHEMICAL CO (JP) 1997-05-28 EP disclosed
US-5326895-A 3-(vinylbenzyloxy)propylsilane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-07-05 US disclosed
US-5326895-A 3-(vinylbenzyloxy)propylsilane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-07-05 US disclosed
US-5326895-A 3-(vinylbenzyloxy)propylsilane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-07-05 US disclosed
EP-0494549-A1 3-(Vinylbenzyloxy)propylsilane compounds, their preparation and polymers thereof Shin-Etsu Chemical Co., Ltd. (JP) 1992-07-15 EP disclosed
EP-0494549-A1 3-(Vinylbenzyloxy)propylsilane compounds, their preparation and polymers thereof Shin-Etsu Chemical Co., Ltd. (JP) 1992-07-15 EP disclosed