Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134211 | 0.84 | TSHR (0.50) | TSHRTDP1L3MBTL1HTTPLK1 | |
| SCHEMBL5092287 | 0.82 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Phthalic Acid SCHEMBL6362073 | 0.80 | TSHR (0.59) | TSHRTDP1L3MBTL1PLK1ALDH1A1 | |
| SCHEMBL2160841 | 0.79 | ALDH1A1 (0.65) | TSHRTDP1L3MBTL1HTTPLK1 | |
| Phthalic Acid SCHEMBL782536 | 0.78 | TSHR (0.58) | TSHRTDP1L3MBTL1PLK1ALDH1A1 | |
| Phthalic Acid SCHEMBL28888377 | 0.78 | TSHR (0.58) | TSHRTDP1L3MBTL1PLK1ALDH1A1 | |
| SCHEMBL5925534 | 0.78 | PLK1 (0.55) | TSHRTDP1L3MBTL1PLK1PTPN11 | |
| SCHEMBL9134691 | 0.78 | KMT2A (0.54) | TSHRHTTPLK1ALDH1A1KMT2A | |
| SCHEMBL27778820 | 0.78 | KMT2A (0.49) | TSHRHTTALDH1A1HSD17B10KMT2A | |
| SCHEMBL1262591 | 0.78 | HDAC3 (0.64) | TSHRPLK1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775128-A1 | PREPARATION OF IMMUNOGENS AND OTHER CONJUGATES OF DRUGS | Dade Chemistry Systems Inc. (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996040664-A2 | PREPARATION OF IMMUNOGENS AND OTHER CONJUGATES OF DRUGS | DADE CHEMISTRY SYSTEMS INC. (US) | 1996-12-19 | — | — | WO | disclosed |