Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1558090 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KDM4EPOLBTSHR | |
| SCHEMBL27530055 | 0.80 | HDAC3 (0.67) | ALDH1A1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL28968193 | 0.80 | HDAC3 (0.67) | ALDH1A1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL5145338 | 0.80 | HDAC3 (0.67) | ALDH1A1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL28973854 | 0.80 | HDAC3 (0.67) | ALDH1A1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL27853144 | 0.80 | HDAC3 (0.67) | ALDH1A1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL8376628 | 0.80 | HDAC6 (0.58) | ALDH1A1HSD17B10KDM4EPOLBHDAC6 | |
| SCHEMBL10785014 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EHDAC6HDAC3 | |
| SCHEMBL143432 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EHDAC6HDAC3 | |
| SCHEMBL5674958 | 0.79 | NAAA (0.70) | ALDH1A1HSD17B10KDM4EPOLBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089515-B2 | Long chain N-alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY (US) | 2015-07-28 | — | — | US | disclosed |
| US-20110184019-A1 | Long chain N-Alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY | 2011-07-28 | — | — | US | disclosed |
| US-7816560-B1 | Long chain n-alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY (US) | 2010-10-19 | — | — | US | disclosed |
| US-20100137365-A1 | Long chain N-alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY | 2010-06-03 | — | — | US | disclosed |
| EP-1210082-A2 | LONG CHAIN N-ALKYL COMPOUNDS AND OXA-DERIVATIVES THEREOF AND USE AS ANTIVIRAL COMPOSITIONS | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001010429-A2 | LONG CHAIN N-ALKYL COMPOUNDS AND OXA-DERIVATIVES THEREOF AND USE AS ANTIVIRAL COMPOSITIONS | THE CHANCELLOR, MASTERS, AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2001-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137365-A1 | Long chain N-alkyl compounds and oxa-derivatives thereof | OXA1L, OTC, PAICS | ALDH1A1 1474/4885HSD17B10 1835/4885KDM4E 2658/4885 |
| US-20110184019-A1 | Long chain N-Alkyl compounds and oxa-derivatives thereof | OXA1L, OTC, PAICS | ALDH1A1 1474/4885HSD17B10 1835/4885KDM4E 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.