Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992391 | 0.87 | MAOB (0.58) | MAOBMAOA | |
| SCHEMBL9720060 | 0.87 | MAOB (0.58) | MAOBMAOA | |
| SCHEMBL18758109 | 0.85 | MAOB (0.62) | MAOBMAOA | |
| SCHEMBL11535006 | 0.84 | MAOB (0.71) | MAOBMAOA | |
| SCHEMBL5260336 | 0.84 | MAOB (0.62) | MAOBMAOA | |
| SCHEMBL7687634 | 0.81 | LSS (0.68) | LSSMEN1KMT2A | |
| SCHEMBL2214019 | 0.81 | MAOB (0.58) | MAOBMAOA | |
| SCHEMBL3849764 | 0.81 | MAOB (0.61) | MAOBMAOA | |
| SCHEMBL9361461 | 0.79 | MAOB (0.49) | MAOBMAOAGAA | |
| SCHEMBL14356128 | 0.79 | MAOB (0.66) | MAOBMAOAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778271-A2 | Aminoalkyl-substituted benzo-heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |