Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 4/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992391 | 1.00 | MAOB (0.58) | MAOBMAOARARARARBTP53 | |
| SCHEMBL18758109 | 0.95 | MAOB (0.62) | MAOBMAOARARARARB | |
| SCHEMBL7814595 | 0.88 | RARB (0.66) | RARARARBTP53TSHRPTPN11 | |
| SCHEMBL7824715 | 0.88 | RARB (0.66) | RARARARBTP53TSHRPTPN11 | |
| SCHEMBL7821266 | 0.88 | RARB (0.66) | RARARARBTP53TSHRPTPN11 | |
| SCHEMBL1583118 | 0.88 | RARB (0.66) | RARARARBTP53TSHRPTPN11 | |
| SCHEMBL9626748 | 0.88 | RARB (0.66) | RARARARBTP53TSHRPTPN11 | |
| SCHEMBL9650203 | 0.87 | THRA (0.52) | RARARARBTP53TSHRPTPN11 | |
| SCHEMBL8760010 | 0.87 | MAOB (0.57) | MAOBMAOA | |
| SCHEMBL9626898 | 0.87 | THRA (0.52) | RARARARBTP53TSHRPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098602-A | Aromatic ester derivatives and fluorophenol ketones | NIPPON MINING CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |