SCHEMBL8760069

SCHEMBL8760069

CCOCCc1ccc(OCCNC(=O)c2cc(C)nn2C)c(C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
MAPT P10636 5/20 0.43
LMNA P02545 4/20 0.40
TP53 P04637 2/20 0.40
HRH3 Q9Y5N1 3/20 0.40
KLKB1 P03952 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
PPARG P37231 3/20 0.39
PPARD Q03181 3/20 0.39
PPARA Q07869 3/20 0.39
ALDH1A1 P00352 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 1/20 0.39
POLB P06746 3/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760124 0.89 GALR3 (0.44) L3MBTL1MAPTLMNATP53HRH3
SCHEMBL9150666 0.82 MAPT (0.39) L3MBTL1MAPTLMNATP53HRH3
SCHEMBL8760420 0.82 SMN1; SMN2 (0.49) L3MBTL1MAPTLMNATP53ALDH1A1
SCHEMBL9151184 0.81 LMNA (0.43) L3MBTL1MAPTLMNATP53ALDH1A1
SCHEMBL8760392 0.80 LMNA (0.47) MAPTLMNATP53ALDH1A1SMN1; SMN2
SCHEMBL8759988 0.80 GAA (0.36) L3MBTL1MAPTLMNATP53HRH3
SCHEMBL8759286 0.80 ALDH1A1 (0.50) L3MBTL1MAPTLMNAALDH1A1HPGD
SCHEMBL9166168 0.80 GALR3 (0.46) L3MBTL1LMNAHRH3PPARGPPARD
SCHEMBL9151802 0.76 LMNA (0.48) L3MBTL1MAPTLMNATP53ALDH1A1
SCHEMBL8759402 0.72 KMT2A (0.41) L3MBTL1MAPTLMNAHRH3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618195-B1 Insecticidal, acaricidal and fungicidal pyrazole phenoxyalkylamin derivatives and process for preparing the same UBE INDUSTRIES (JP) 1997-06-04 EP disclosed
US-5380744-A Insecticides, miticides or fungicides UBE INDUSTRIES, LTD. (JP) 1995-01-10 US disclosed
EP-0618195-A1 Insecticidal, acaricidal and fungicidal pyrazole phenoxyalkylamin derivatives and process for preparing the same UBE INDUSTRIES, LTD. (JP) 1994-10-05 EP disclosed