Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benmoxin SCHEMBL8759658 | 0.86 | GPR139 (0.55) | SMN1; SMN2NPC1RAB9AGPR139PTGS2 | |
| Benmoxin SCHEMBL54431 | 0.86 | GPR139 (0.55) | SMN1; SMN2NPC1RAB9AGPR139PTGS2 | |
| Benmoxin SCHEMBL8760295 | 0.86 | GPR139 (0.55) | SMN1; SMN2NPC1RAB9AGPR139PTGS2 | |
| SCHEMBL2654331 | 0.83 | NR1H4 (0.54) | SMN1; SMN2NPC1RAB9AGPR139ALDH1A1 | |
| SCHEMBL8759636 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL8759672 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL8760655 | 0.79 | PTGS2 (0.60) | SMN1; SMN2NPC1RAB9APTGS2ALDH1A1 | |
| SCHEMBL8760263 | 0.79 | PTGS2 (0.60) | SMN1; SMN2NPC1RAB9APTGS2ALDH1A1 | |
| SCHEMBL8759664 | 0.77 | MEN1 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL8760609 | 0.77 | MEN1 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631571-B1 | PREPARATION OF OPTICALLY ACTIVE HYDRAZINES AND AMINES | DU PONT (US) | 1997-06-04 | — | — | EP | disclosed |
| US-5543571-A | Preparation of optically active hydrazines and amines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-06 | — | — | US | disclosed |
| US-5426223-A | Hydrogenation of n-acyl hydrazones in presence of catalyst comprising complex pf transition metal bonded to phosphine ligands | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-06-20 | — | — | US | disclosed |
| US-5250731-A | Asymmetric hydrogenation of N-acylhydrazones to N-acylhydrazines in presence of chiral phospholane complex | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-10-05 | — | — | US | disclosed |
| WO-1993019040-A1 | PREPARATION OF OPTICALLY ACTIVE HYDRAZINES AND AMINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-30 | — | — | WO | disclosed |