Thiohydantoin

Thiohydantoin

SCHEMBL8760331

O=C1CNC(=S)N1.O=c1cc[nH][nH]1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.31
ALDH1A1 P00352 1/20 0.30
AOC3 Q16853 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiohydantoin SCHEMBL27396584 0.76 MAPT (0.33)
Thiohydantoin SCHEMBL3520254 0.76
Thiohydantoin SCHEMBL31955553 0.76
SCHEMBL57548 0.73
Thiohydantoin SCHEMBL28357993 0.72 GSK3A (0.31)
Biphenyl SCHEMBL27404603 0.72 SIRT2 (0.42) ALDH1A1
Uracil SCHEMBL6838842 0.71 CRBN (0.50) TP53
Hydrochloric Acid SCHEMBL7215896 0.71
Methane SCHEMBL190372 0.71 ALDH1A1 (0.50) TP53ALDH1A1AOC3
SCHEMBL17474379 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0774122-A1 MEROCYANINE DYE PROTEIN STAINS MOLECULAR PROBES, INC. (US) 1997-05-21 EP disclosed
US-5616502-A QUANTITATIVE, COLORIMETRIC ANALYSIS OF POLYAMINO ACIDS MOLECULAR PROBES, INC. (US) 1997-04-01 US disclosed
WO-1996036882-A1 MEROCYANINE DYE PROTEIN STAINS MOLECULAR PROBES, INC. (US) 1996-11-21 WO disclosed
US-4857445-A Direct positive photo-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1989-08-15 US disclosed