Thiohydantoin

Thiohydantoin

SCHEMBL8760334

O=C1C=CN=N1.O=C1CNC(=S)N1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiohydantoin SCHEMBL27396584 0.75 MAPT (0.33)
Thiohydantoin SCHEMBL31955553 0.74
Thiohydantoin SCHEMBL3520254 0.74
SCHEMBL57549 0.72
Thiohydantoin SCHEMBL28357993 0.71 GSK3A (0.31)
Hydrochloric Acid SCHEMBL1554036 0.70
Ammonia Solution, Strong SCHEMBL3496230 0.70
Methane SCHEMBL222390 0.70
Lithium SCHEMBL17474380 0.70
Methane SCHEMBL190374 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0774122-A1 MEROCYANINE DYE PROTEIN STAINS MOLECULAR PROBES, INC. (US) 1997-05-21 EP disclosed
US-5616502-A QUANTITATIVE, COLORIMETRIC ANALYSIS OF POLYAMINO ACIDS MOLECULAR PROBES, INC. (US) 1997-04-01 US disclosed
WO-1996036882-A1 MEROCYANINE DYE PROTEIN STAINS MOLECULAR PROBES, INC. (US) 1996-11-21 WO disclosed