Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57549 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL3496230 | 0.94 | — | — | |
| Lithium SCHEMBL17474380 | 0.94 | — | — | |
| SCHEMBL12814542 | 0.86 | — | — | |
| Naphthalene SCHEMBL3488504 | 0.82 | CYP2A6 (0.38) | — | |
| Chlorobenzene SCHEMBL11324480 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL1229197 | 0.75 | — | — | |
| Imidazole SCHEMBL10529232 | 0.73 | ALDH1A1 (0.50) | — | |
| Oxazole SCHEMBL9345575 | 0.73 | — | — | |
| Quinoline SCHEMBL1647025 | 0.70 | ALDH1A1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402506-B | Yellow reactive dye and preparation method thereof | 江苏德美科化工有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-117776546-A | Anti-reflection glass | 福美化学工业株式会社 | 2024-03-29 | — | — | CN | disclosed |
| CN-117402506-A | Yellow reactive dye and preparation method thereof | 江苏德美科化工有限公司 | 2024-01-16 | — | — | CN | disclosed |
| EP-2263642-B1 | Colouring bleaches | HENKEL AG & CO KGAA (DE) | 2020-04-15 | — | — | EP | disclosed |
| CN-107176957-B | Chiral pyrazolone spiro [ ethylenethiourea ] spirooxindole compound and derivative thereof | 大连理工大学 | 2019-10-11 | — | — | CN | disclosed |
| CN-107382867-A | 4-isothiocyanato pyrazolones | 大连理工大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-107176957-A | Chiral pyrazolone spiro [ ethylenethiourea ] spirooxindole compound and derivative thereof | 大连理工大学 | 2017-09-19 | — | — | CN | disclosed |
| US-20120322842-A1 | HETEROCYCYL-SUBSTITUTED-ALKYLAMINOPHENYL DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2012-12-20 | — | — | US | disclosed |
| US-20120264799-A1 | INDANE-AMINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE ,S.A. (ES) | 2012-10-18 | — | — | US | disclosed |
| EP-2486016-A1 | HETEROCYCYL-SUBSTITUTED-ALKYLAMINO PHENYL DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042302-A1 | HETEROCYCYL-SUBSTITUTED-ALKYLAMINO PHENYL DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042343-A1 | INDANE-AMINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2011-04-14 | — | — | WO | disclosed |
| EP-2308850-A1 | Heterocycyl-substituted-alkylamino phenyl derivatives, their preparation and use as medicaments | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2011-04-13 | — | — | EP | disclosed |
| EP-2308849-A1 | Indane-amine derivatives, their preparation and use as medicaments | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2011-04-13 | — | — | EP | disclosed |
| CN-101679374-A | Hydrazide compound and harmful arthropod-controlling agent containing the same | SUMITOMO CHEMICAL CO | 2010-03-24 | — | — | CN | disclosed |
| EP-2148876-A1 | PYRAZOLONE DERIVATIVES AS PDE4 INHIBITORS | Nycomed GmbH (DE) | 2010-02-03 | — | — | EP | disclosed |
| CN-101384238-A | Dye-containing pellets and use thereof | WELLA AG (US) | 2009-03-11 | — | — | CN | disclosed |
| CN-101384303-A | Coloring agent for coloring keratin fibers | WELLA AG (US) | 2009-03-11 | — | — | CN | disclosed |
| WO-2008138939-A1 | PYRAZOLONE DERIVATIVES AS PDE4 INHIBITORS | NYCOMED GMBH (DE) | 2008-11-20 | — | — | WO | disclosed |
| US-6616706-B1 | Phase inversion temperature emulsion of oil and as an emulsifier an oligoglycoside, anionic surfactant, esterquat, polyolpoly-12-hydroxystearate, fatty alcohol, or polyoxyethylene fatty alcohol ether | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-09-09 | — | — | US | disclosed |