Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.49 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940 | 0.81 | ACHE (0.56) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL5366068 | 0.80 | TSHR (0.46) | TSHRZDHHC20ZDHHC2EPHX1FAAH | |
| SCHEMBL8769221 | 0.80 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL6332081 | 0.80 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL14328774 | 0.80 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL6332791 | 0.80 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL8769159 | 0.80 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL11519960 | 0.80 | TSHR (0.61) | TSHREPHX1ACHE | |
| SCHEMBL10349440 | 0.80 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL8769636 | 0.80 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592552-B1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | DU PONT (US) | 1997-05-28 | — | — | EP | claimed |
| US-5559267-A | ENANTIOMORPHS, STEREOCHEMICAL CONTROL AND ASSYMETRIC INDUCTION, HYDROGENATION OF UNSATURATED ESTERS, COORDINATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | claimed |
| EP-0592552-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES. | DU PONT (US) | 1994-04-20 | — | — | EP | claimed |