Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760455 | 0.80 | TSHR (0.50) | TSHRZDHHC20ZDHHC2EPHX1FAAH | |
| SCHEMBL5363816 | 0.79 | EPHX1 (0.60) | ZDHHC20ZDHHC2EPHX1CASP2 | |
| SCHEMBL5363824 | 0.79 | EPHX1 (0.60) | ZDHHC20ZDHHC2EPHX1CASP2 | |
| SCHEMBL29940 | 0.78 | ACHE (0.56) | TSHRZDHHC20ZDHHC2EPHX1EPHX2 | |
| SCHEMBL8769221 | 0.76 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1EPHX2 | |
| SCHEMBL6332081 | 0.76 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1EPHX2 | |
| SCHEMBL8769159 | 0.76 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1EPHX2 | |
| SCHEMBL14328774 | 0.76 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1EPHX2 | |
| SCHEMBL6332791 | 0.76 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1EPHX2 | |
| SCHEMBL10349440 | 0.76 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007153757-A | METHOD FOR PRODUCING 1,2-DIARYLAMINO-1,2-ETHYLENEDICARBOXYLIC ACID ALKYL ESTER | DAINIPPON INK & CHEM INC | 2007-06-21 | — | — | JP | disclosed |