Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3713052 | 0.78 | POLB (0.58) | POLBNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL3721248 | 0.77 | POLB (0.60) | POLBNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4592734 | 0.77 | POLB (0.56) | POLBNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL14698727 | 0.76 | POLB (0.52) | POLBNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL5190567 | 0.72 | POLB (0.50) | POLBMEN1KMT2ACHRNA7 | |
| SCHEMBL17372632 | 0.71 | POLB (0.49) | POLBNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4725610 | 0.68 | P2RX7 (0.55) | POLBNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL656655 | 0.68 | POLB (0.97) | POLBNPC1RAB9ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL28769179 | 0.68 | POLB (0.45) | POLBCHRNA7 | |
| SCHEMBL7504156 | 0.67 | POLB (0.93) | POLBNPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773937-A1 | NOVEL ARYL PIPERAZINE-DERIVED PIPERAZIDE DERIVATIVES, METHODS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | PIERRE FABRE MEDICAMENT (FR) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996002525-A1 | NOVEL ARYL PIPERAZINE-DERIVED PIPERAZIDE DERIVATIVES, METHODS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | PIERRE FABRE MEDICAMENT (FR) | 1996-02-01 | — | — | WO | disclosed |